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1

Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria

Saier, Milton H., Paulsen, Ian T., Sliwinski, Marek K., Pao, Stephanie S., Skurray, Ronald A., Nikaido, Hiroshi

Journal:

The FASEB Journal

Year:

1998

Language:

english

File:

PDF, 901 KB

english, 1998

2

The multidrug efflux protein NorM is a prototype of a new family of transporters

Melissa H. Brown, Ian T. Paulsen, Ronald A. Skurray

Journal:

Molecular Microbiology

Year:

1999

Language:

english

File:

PDF, 938 KB

english, 1999

3

Staphylococcus aureus multiresistance plasmid pSK41: analysis of the replication region, initiator protein binding and antisense RNA regulation

Stephen M. Kwong, Ronald A. Skurray, Neville Firth

Journal:

Molecular Microbiology

Year:

2004

Language:

english

File:

PDF, 467 KB

english, 2004

4

Beginning a transcriptional analysis of the leading region in F plasmid DNA transfer

David S. Cram, Dario Berardino, Ronald A. Skurray

Journal:

Molecular Genetics and Genomics

Year:

1982

Language:

english

File:

PDF, 298 KB

english, 1982

5

Tn4001: A gentamicin and kanamycin resistance transposon inStaphylococcus aureus

Bruce R. Lyon, John W. May, Ronald A. Skurray

Journal:

Molecular Genetics and Genomics

Year:

1984

Language:

english

File:

PDF, 439 KB

english, 1984

6

A protein family associated with filament biogenesis in bacteria

Neville Firth, Ronald A. Skurray

Journal:

Molecular Microbiology

Year:

1995

Language:

english

File:

PDF, 1.18 MB

english, 1995

7

The SMR family: a novel family of multidrug efflux proteins involved with the efflux of lipophilic drugs

Ian T. Paulsen, Ronald A. Skurray, Roland Tam, Milton H. Saier Jr, Raymond J. Turner, Joel H. Weiner, Edward B. Goldberg, Leonas L. Grinius

Journal:

Molecular Microbiology

Year:

1996

Language:

english

File:

PDF, 954 KB

english, 1996

8

Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus

Tim G. Littlejohn, Ian T. Paulsen, Matthew T. Gillespie, Jan M. Tennent, Melvin Midgley, I. Gwyn Jones, Amarjit S. Purewal, Ronald A. Skurray

Journal:

FEMS Microbiology Letters

Year:

1992

Language:

english

File:

PDF, 363 KB

english, 1992

9

Functional effects of intramembranous proline substitutions in the staphylococcal multidrug transporter QacA

Karl A. Hassan, Melanie Galea, Jingqin Wu, Bernadette A. Mitchell, Ronald A. Skurray, Melissa H. Brown

Journal:

FEMS Microbiology Letters

Year:

2006

Language:

english

File:

PDF, 567 KB

english, 2006

10

A multimer resolution system contributes to segregational stability of the prototypical staphylococcal conjugative multiresistance plasmid pSK41

Rebecca J. LeBard, Slade O. Jensen, Isabel A. Arnaiz, Ronald A. Skurray, Neville Firth

Journal:

FEMS Microbiology Letters

Year:

2008

Language:

english

File:

PDF, 434 KB

english, 2008

11

Segrosome structure revealed by a complex of ParR with centromere DNA

Schumacher, Maria A., Glover, Tiffany C., Brzoska, Anthony J., Jensen, Slade O., Dunham, Thomas D., Skurray, Ronald A., Firth, Neville

Journal:

Year:

2007

Language:

english

File:

PDF, 1.40 MB

english, 2007

12

Multidrug Resistance Plasmid pSK108 from Coagulase-Negative Staphylococci; Relationships to Staphylococcus aureus qacC Plasmids

Amornrut Leelaporn, Neville Firth, Ian T. Paulsen, Anusha Hettiaratchi, Ronald A. Skurray

Journal:

Year:

1995

File:

PDF, 275 KB

1995

13

Molecular Analysis of a Mobilizable Theta-Mode Trimethoprim Resistance Plasmid from Coagulase-Negative Staphylococci

Sumalee Apisiridej, Amornrut Leelaporn, Carol D. Scaramuzzi, Ronald A. Skurray, Neville Firth

Journal:

Year:

1997

Language:

english

File:

PDF, 462 KB

english, 1997

14

Nucleotide Sequence of the F Plasmid Leading Region

Neil P. Manwaring, Ronald A. Skurray, Neville Firth

Journal:

Year:

1999

Language:

english

File:

PDF, 202 KB

english, 1999

15

The POT family of transport proteins

Ian T. Paulsen, Ronald A. Skurray

Journal:

Trends in Biochemical Sciences

Year:

1994

Language:

english

File:

PDF, 150 KB

english, 1994

16

Analysis of the prototypical Staphylococcus aureus multiresistance plasmid pSK1

Slade O. Jensen, Sumalee Apisiridej, Stephen M. Kwong, Yee Hwa Yang, Ronald A. Skurray, Neville Firth

Journal:

Year:

2010

Language:

english

File:

PDF, 645 KB

english, 2010

17

Analysis and characterization of the IncFV plasmid pED208 transfer region

Jun Lu, Jan Manchak, William Klimke, Colin Davidson, Neville Firth, Ronald A Skurray, Laura S Frost

Journal:

Year:

2002

Language:

english

File:

PDF, 356 KB

english, 2002

18

Functional analyses reveal an important role for tyrosine residues in the staphylococcal multidrug efflux protein QacA

Jingqin Wu, Karl A Hassan, Ronald A Skurray, Melissa H Brown

Journal:

BMC Microbiology

Year:

2008

Language:

english

File:

PDF, 394 KB

english, 2008

19

Transcriptional regulation of multidrug efflux pumps in bacteria

Steve Grkovic, Melissa H. Brown, Ronald A. Skurray

Journal:

Seminars in Cell & Developmental Biology

Year:

2001

Language:

english

File:

PDF, 2.48 MB

english, 2001

20

Identification of suitable internal controls to study expression of a Staphylococcus aureus multidrug resistance system by quantitative real-time PCR

Torsten Theis, Ronald A. Skurray, Melissa H. Brown

Journal:

Journal of Microbiological Methods

Year:

2007

Language:

english

File:

PDF, 277 KB

english, 2007

21

Optimized production and analysis of the staphylococcal multidrug efflux protein QacA

Karl A. Hassan, Zhiqiang Xu, Ryan E. Watkins, Richard G. Brennan, Ronald A. Skurray, Melissa H. Brown

Journal:

Protein Expression and Purification

Year:

2009

Language:

english

File:

PDF, 352 KB

english, 2009

22

Mobile elements in the evolution and spread of multiple-drug resistance in staphylococci

Neville Firth, Ronald A. Skurray

Journal:

Drug Resistance Updates

Year:

1998

Language:

english

File:

PDF, 1.01 MB

english, 1998

23

Construction and BamHI analysis of chimeric plasmids containing EcoRI DNA fragments of the F sex factor

Ronald A. Skurray, Haruko Nagaishi, Alvin J. Clark

Journal:

Year:

1978

Language:

english

File:

PDF, 3.99 MB

english, 1978

24

4′,4′' Adenyltransferase activity on conjugative plasmids isolated from Staphylococcus aureus is encoded on an integrated copy of pUB110

Mary E. Byrne, Matthew T. Gillespie, Ronald A. Skurray

Journal:

Year:

1991

Language:

english

File:

PDF, 1.00 MB

english, 1991

25

Analysis of a transfer region from the staphylococcal conjugative plasmid pSK41

Firth, Neville, Ridgway, Karyn P., Byrne, Mary E., Fink, Peter D., Johnson, Luke, Paulsen, Ian T., Skurray, Ronald A.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.79 MB

english, 1993

26

Topology, structure and evolution of two families of proteins involved in antibiotic and antiseptic resistance in eukaryotes and prokaryotes â an analysis

Paulsen, Ian T., Skurray, Ronald A.

Journal:

Year:

1993

Language:

english

File:

PDF, 4.50 MB

english, 1993

27

IS257 from Staphylococcus aureus: member of an insertion sequence superfamily prevalent among Gram-positive and Gram-negative bacteria

Rouch, Duncan A., Skurray, Ronald A.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.11 MB

english, 1989

28

Interactions of the QacR Multidrug-Binding Protein with Structurally Diverse Ligands: Implications for the Evolution of the Binding Pocket †

Grkovic, Steve, Hardie, Kate M., Brown, Melissa H., Skurray, Ronald A.

Journal:

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

29

Biochemical Characterization of the Multidrug Regulator QacR Distinguishes Residues That Are Crucial to Multidrug Binding and Induction of qacA Transcription

Peters, Kate M., Sharbeen, George, Theis, Torsten, Skurray, Ronald A., Brown, Melissa H.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.61 MB

english, 2009

30

Membrane transport proteins: implications of sequence comparisons

Griffith, Jeffrey K., Baker, Michael E., Rouch, Duncan A., Page, Malcolm G.P., Skurray, Ronald A., Paulsen, Ian T., Chater, Keith F., Baldwin, Stephen A., Henderson, Peter J.F.

Journal:

Current Opinion in Cell Biology

Year:

1992

Language:

english

File:

PDF, 1.24 MB

english, 1992

31

Structure and evolution of a family of genes encoding antiseptic and disinfectant resistance in Staphylococcus aureus

Littlejohn, Tim G., DiBerardino, Dario, Messerotti, Linda J., Spiers, Samantha J., Skurray, Ronald A.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.06 MB

english, 1991

32

Characterisation of sin, a potential recombinase-encoding gene from Staphylococcus aureus

Paulsen, Ian T., Gillespie, Matthew T., Littlejohn, Tim G., Hanvivatvong, Orawadee, Rowland, Sally-J., Dyke, Keith G.H., Skurray, Ronald A.

Journal:

Year:

1994

Language:

english

File:

PDF, 806 KB

english, 1994

33

Nucleotide sequence analysis of IS256 from the Staphylococcus aureus gentamicin-tobramycin-kanamycin-resistance transposon Tn4001

Byrne, Mary E., Rouch, Duncan A., Skurray, Ronald A.

Journal:

Year:

1989

Language:

english

File:

PDF, 711 KB

english, 1989

34

Topology, structure and evolution of two families of proteins involved in antibiotic and antiseptic resistance in eukaryotes and prokaryotes — an analysis

Paulsen, Ian T., Skurray, Ronald A.

Journal:

Year:

1993

Language:

english

File:

PDF, 60 KB

english, 1993

35

Sequence and conservation of genes at the distal end of the transfer region on plasmids F and R6-5

Cram, David S., Loh, Sue M., Cheah, Keat-Chye, Skurray, Ronald A.

Journal:

Year:

1991

Language:

english

File:

PDF, 711 KB

english, 1991

36

Molecular Cloning of DNA from F Sex Factor of Escherichia coli K-12

Ronald A. Skurray, Haruko Nagaishi and Alvin J. Clark

Journal:

Proceedings of the National Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 1.54 MB

english, 1976

37

Glycine-Rich Transmembrane Helix 10 in the Staphylococcal Tetracycline Transporter TetA(K) Lines a Solvent-Accessible Channel †

Hassan, Karl A., Robinson, Katie L., Smith, Alison N., Gibson, Joanne H., Skurray, Ronald A., Brown, Melissa H.

Journal:

Year:

2006

Language:

english

File:

PDF, 351 KB

english, 2006

38

QacR−Cation Recognition Is Mediated by a Redundancy of Residues Capable of Charge Neutralization †

Peters, Kate M., Schuman, Jason T., Skurray, Ronald A., Brown, Melissa H., Brennan, Richard G., Schumacher, Maria A.

Journal:

Year:

2008

Language:

english

File:

PDF, 5.34 MB

english, 2008

39

Active Export Proteins Mediating Drug Resistance in Staphylococci

Hassan, Karl A., Skurray, Ronald A., Brown, Melissa H.

Journal:

Journal of Molecular Microbiology and Biotechnology

Year:

2007

Language:

english

File:

PDF, 319 KB

english, 2007

40

Nucleotide sequence of the blaZ gene of the Staphylococcus aureus β-lactamase transposon Tn 4002

Gillespie, Matthew T., Skurray, Ronald A.

Journal:

Nucleic Acids Research

Year:

1989

Language:

english

File:

PDF, 74 KB

english, 1989

41

A Single Acidic Residue Can Guide Binding Site Selection but Does Not Govern QacR Cationic-Drug Affinity

Peters, Kate M., Brooks, Benjamin E., Schumacher, Maria A., Skurray, Ronald A., Brennan, Richard G., Brown, Melissa H., van Veen, Hendrik W.

Journal:

Year:

2011

Language:

english

File:

PDF, 1007 KB

english, 2011

42

Dynamic Filament Formation by a Divergent Bacterial Actin-Like ParM Protein

Brzoska, Anthony J., Jensen, Slade O., Barton, Deborah A., Davies, Danielle S., Overall, Robyn L., Skurray, Ronald A., Firth, Neville, Hayes, Finbarr

Journal:

Year:

2016

Language:

english

File:

PDF, 716 KB

english, 2016

43

Staphylococcal Plasmids, Transposable and Integrative Elements

Firth, Neville, Jensen, Slade O., Kwong, Stephen M., Skurray, Ronald A., Ramsay, Joshua P.

Journal:

Microbiology Spectrum

Year:

2018

Language:

english

File:

PDF, 3.02 MB

english, 2018

44

QacA Multidrug Efflux Pump fromStaphylococcus aureus: Comparative Analysis of Resistance to Diamidines, Biguanidines, and Guanylhydrazones

Mitchell, Bernadette A., Brown, Melissa H., Skurray, Ronald A.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

1998

File:

PDF, 97 KB

1998

45

Evolutionary origins of multidrug and drugâspecific efflux pumps in bacteria

Saier, Milton H., Paulsen, Ian T., Marek, K. sliwinski, Pao, Stephanie S., Ronald, A. skurray, Nikaido, Hiroshi

Journal:

The FASEB Journal

Year:

1998

File:

PDF, 814 KB

1998